Kelly Tan
Collaboratice scientifique - Ambizione Fellow until October 2014
Publications :
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Lalive AL, Munoz MB, Bellone C, Slesinger PA, Lüscher C, Tan KR. Firing modes of dopamine neurons drive bidirectional GIRK channel plasticity. J Neurosci. 2014 Apr 9;34(15):5107-14.
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Brown MT, Tan KR, O'Connor E, Nikonenko I, Muller D. Lüscher C. Ventral tegmental area GABA projections pause accumbal cholinergic interneurons to enhance associative learning. Nature 2012, doi:10.1038/nature11657, Published online November 25, 2012.
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Tan KR, Yvon C, Turiault M, Mirzabekov JJ, Doehner J, Labouèbe G, Deisseroth K, Tye KM, Lüscher C. GABA neurons of the VTA drive conditioned place aversion. Neuron. 2012 Mar 22;73(6):1173-83. Epub 2012 Mar 21.
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Claire L. Padgett, Arnaud L. Lalive, Kelly R. Tan, Miho Terunuma, Michaelanne B. Munoz, Menelas N. Pangalos, Jose Martinez-Hernandez, Masahiko Watanabe, Stephen J. Moss, Rafael Lujan, Christian Lüscher and Paul A. Slesinger. Methamphetamine-Evoked Depression of GABA(B) Receptor Signaling in GABA Neurons of the VTA. Neuron. 2012 Mar 8;73(5):978-89.
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Arnaud L. Lalive, Uwe Rudolph, Christian Lüscher, Kelly R. Tan. Is there a way to curb benzodiazepine addiction? Swiss Med Wkly. 2011 Oct 19;141:w13277.
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Tan KR, Rudolph U, Lüscher C. Hooked on benzodiazepines: GABAA receptor subtypes and addiction Trends Neurosci. 2011 Apr;34(4):188-97. Epub 2011 Feb 25. Review.
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Kelly R. Tan, Matthew Brown, Gwenaël Labouèbe, Cédric Yvon, Cyril Creton, Jean-Marc Fritschy, Uwe Rudolph & Christian Lüscher. Neural bases for addictive properties of benzodiazepines. Nature 463, 469-474. Epub 2010 Feb 11.
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Tan KR, Baur R, Charon S, Goeldner M, Sigel E. Relative positioning of diazepam in the benzodiazepine-binding-pocket of GABA receptors. J Neurochem. 2009 Dec; 111(5):1264-73. Epub 2009 Oct 5.
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Baur R, Tan KR, Lüscher BP, Gonthier A, Goeldner M, Sigel E. Covalent modification of GABAA receptors isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs. J Neurochem. 2008 Sep;106(6):2353-63. Epub 2008 Jul 15.
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K. R. Tan, R. Baur, A. Gonthier, M. Goeldner, E. Sigel “ Two neighboring residues of loop A of the alpha-1 subunit point towards the benzodiazepine binding site of GABAA receptors. FEBS Lett. 2007 Oct;581(24):4718-22.
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K. R. Tan, A. Gonthier, R. Baur, M. Ernst, M. Goeldner, E. Sigel “ Proximity-accelerated chemical coupling reaction in the benzodiazepine binding site of GABAA receptors: superposition of different allosteric modulators” J. Biol. Chem. 2007 Sept 7;282(36):26316- 25.
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S. Laffray*, K. Tan*, J. Dulluc, R. Bouali-Benazzouz, A. R. Calver, F. Nagy, M. Landry “Dissociation and trafficking of rat GABAB receptor heterodimer upon chronic capsaicin stimulation” Eur. J. Neurosci. 2007 Mar;25(5):1402-16.
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K. Tan, C. Guibert, V. Neaud, J. Rosenbaum “ Hepatitis C virus proteins do not directly trigger fibrogenic events in cultured human liver myofibroblasts.” Viral. Hepat. 2003 Nov;10(6):427-32.